7714 Conner Rd #106, Powell, TN 37849, USA
⭐ 4.9(517)
Glow Medical Aesthetics, Weight Loss, Wellness & Primary Care Knoxville is a medical spa offering GLP-1 weight loss treatments in Knoxville, Tennessee.
SemaglutideTirzepatideIn-Person
Weight Loss Clinics in Knoxville, Tennessee
Looking for a weight loss clinic that prescribes GLP-1 medications? Our directory lists 60 verified providers serving Knoxville, Tennessee (198,722 residents · 36.7% adult obesity).
Each clinic below offers GLP-1 weight-loss medications including Ozempic, Wegovy, Mounjaro, and Zepbound. Compare ratings, services, and pricing — then book directly or via our partner directory at GLP1Maps.com.
Top 10 GLP-1 Clinics in Knoxville
10315 Kingston Pike, Knoxville, TN 37922, USA
⭐ 5(437)
Jessica Ellam Medical Aesthetics is a medical spa offering GLP-1 weight loss treatments in Knoxville, Tennessee.
SemaglutideTirzepatideIn-Person
10918 Kingston Pike, Knoxville, TN 37934, USA
⭐ 5(31)
Be Well of Knoxville Weight Loss & Anti-Aging is a medical spa offering GLP-1 weight loss treatments in Knoxville, Tennessee.
SemaglutideTirzepatideIn-Person
7525 Brickyard Rd, Powell, TN 37849, USA
⭐ 5(201)
The Refinery: Medical Aesthetics and Wellness is a medical spa offering GLP-1 weight loss treatments in Knoxville, Tennessee.
SemaglutideTirzepatideIn-Person
Knoxville, TN
⭐ 4.6
Sarah Hitchcox Aesthetics — Premier Knoxville med spa with 2 locations: 5113 Kingston Pike (Bearden) & 102 S Campbell Station Rd (Farragut). (865) 489-8008. 4.9H
OzempicMounjaroIn-Person
Pricing: ~half brand-name price
Knoxville, TN
⭐ 4.5
New Vision Weight Loss Clinic — Voted Knoxville’s Best Weight Loss Clinic 8 consecutive years. Now accepting new patients by appointment. 4.9H
SemaglutideIn-Person
Knoxville, TN
⭐ 4.4
Dr. Dean Kleto, MD — Board-certified, fellowship-trained plastic surgeon offering GLP-1 medical weight loss + body contouring. (865) 524-2442. 4.8H
SemaglutideIn-Person
Knoxville, TN
⭐ 4.4
Weight Loss Knox — Physician-supervised semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound). Average 15–22% body weight loss. 4.8H
OzempicWegovyMounjaroZepboundIn-Person
Knoxville, TN
⭐ 4.3
Weight to Go Weight Loss — Clinics in Knoxville, Turkey Creek, Sevierville, Oneida & more. Nutritional counseling + GLP-1. 4.7H
SemaglutideIn-Person
Knoxville, TN
⭐ 4.2
Interstate Health Knoxville — Physician-led semaglutide & tirzepatide. Flexible scheduling for busy adults. 4.7H
OzempicMounjaroIn-Person
More GLP-1 Resources
Browse All GLP-1 Clinics →
Full directory of verified providers on GLP1Maps.com
Clinic Owner? →
Get an AI Receptionist that books patients 24/7 — from GLP1Receptionist.com
New to GLP-1? →
Read Shep's Method — patient guide to GLP-1 success at ShepsMethod.com
Independent network of GLP-1 resources serving Knoxville and patients across the U.S.
What to Look for in a GLP-1 Clinic
Choosing the right GLP-1 provider in Knoxville matters. Look for clinics that offer:
- Board-certified physicians or NPs with experience in metabolic medicine
- FDA-approved medications (Ozempic, Wegovy, Mounjaro, Zepbound) — not unverified compounded versions
- Comprehensive lab work before starting therapy
- Ongoing monitoring — weight, side effects, dose adjustments
- Transparent pricing — monthly costs, insurance acceptance
- Real reviews with details — clinics with text-rich patient reviews are more trustworthy than star-only ratings
GLP-1 Medications Explained
GLP-1 receptor agonists work by mimicking a hormone that regulates appetite and blood sugar. The main options:
- Ozempic & Wegovy — both contain semaglutide. Ozempic is FDA-approved for type 2 diabetes; Wegovy for chronic weight management.
- Mounjaro & Zepbound — both contain tirzepatide (a dual GIP/GLP-1 agonist). Mounjaro for diabetes; Zepbound for weight loss.
- Compounded GLP-1s — Following the April 2026 FDA 503B ruling, compounded GLP-1 medications are no longer available from most pharmacies. Stick with FDA-approved brand-name medications from verified clinics.
Cost & Insurance in Tennessee
TennCare covers GLP-1 for diabetes only.
For state regulation info, see the Tennessee Medical Board.
Frequently Asked Questions
How many GLP-1 clinics are in Knoxville?
Our directory lists 60 verified GLP-1 clinics in the Knoxville area, with rankings based on patient reviews, services offered, and verified provider status.
Does insurance cover GLP-1 medications in Tennessee?
TennCare covers GLP-1 for diabetes only.
Are compounded GLP-1 medications still available?
Following the FDA's April 2026 503B ruling, compounded semaglutide and tirzepatide are no longer available from most U.S. pharmacies. Most clinics now prescribe FDA-approved Ozempic, Wegovy, Mounjaro, or Zepbound.